Per profootballtalk.com alex smith has a sprained middle finger on his throwing hand. They are saying he will be fine and it is not a big deal - but any Q will tell you injuries to your throwing hand can be potentially dangerous. If it just hurts him on one or two throws and they come out ducks we may get a pick or two. I don't think this will be the same as romo's hand last year but one never knows.
Also one weapon the giants must be ready for is the wildcat with colin kapernick - kid has been very good this year.